Publications since 2008
2012
Schwab ME, Buchli A (2012). Plug the real brain drain. Nature 483:267-268.
2011
Pernet V, Joly S, Dalkara D, Schwarz O, Christ F, Schaffer D, Flannery JG, Schwab ME (2011). Neuronal Nogo-A upregulation does not contribute to ER stress-associated apoptosis but participates in the regenerative response in the axotomized adult retina. Cell Death Differ. 2011 Dec 23. doi: 10.1038/cdd.2011.191. [Epub ahead of print] PMID:22193546 [PubMed - as supplied by publisher]
Schnell L, Hunanyan AS, Bowers WJ, Horner PJ, Federoff HJ, Gullo M, Schwab ME, Mendell LM, Arvanian VL. (2011). Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. Eur J Neurosci. 2011 Oct;34(8):1256-67. doi: 10.1111/j.1460-9568.2011.07862.x. Epub 2011 Oct 13.
Starkey ML, Bleul C, Maier IC, and Schwab ME (2011). Rehabilitative training following unilateral pyramidotomy in adult rats improves forelimb function in a non-task-specific way. Experimental Neurology 232(1): 81-89.
Gonzenbach RR, Zoerner B, Schnell L, Weinmann O, Mir A, and Schwab ME (2011). Delayed anti-Nogo-A antibody application after spinal cord injury shows progressive loss of responsiveness. J Neurotrauma. (E-pub ahead of print.)
Ghosh A, Peduzzi S, Snyder M, Schneider R, Starkey M, and Schwab ME (2011). Heterogeneous Spine Loss in Layer 5 Cortical Neurons after Spinal Cord Injury. Cereb Cortex. (E-pub ahead of print.)
Filli L, Zorner B, Weinmann O, and Schwab ME (2011). Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Sequard syndrome. Brain 134: 2261-2273.
Starkey ML, Schwab ME (2011). Anti-Nogo-A and training: Can one plus one equal three? Exp. Neurol. (E-pub ahead of print.)
Delekate A, Zagrebelsky M, Kramer S, Schwab ME, and Korte M (2011). Nogo A restricts synaptic plasticity in the adult hippocampus on a fast time scale. Proc Natl Acad Sci USA 108: 2569-2574.
Tsai SY, Papadopoulos CM, Schwab ME, Kartje GL (2011). Delayed anti-nogo-a therapy improves function after chronic stroke in adult rats. Stroke 42:186-90.
2010
Schwab ME (2010) How hard is the CNS hardware? Nat Neurosci 13:1444-6.
Schwab ME. (2010) Functions of Nogo proteins and their receptors in the vervous system. Nat Rev Nerusoci. 11(12): 799-811, Epub 2010 Nov 3.
Zagrebelsky M, Schweigreiter R, Bandtlow CE, Schwab ME, Korte M. (2010) Nogo-A stabilizes the architecture of hippocampal neurons. J Neurosci. 30(40):13220-34.
Zörner B, Filli L, Starkey ML, Gonzenbach R, Kasper H, Röthlisberger M, Bolliger M, Schwab ME (2010) Profiling locomotor recovery: comprehensive quantification of impairments after CNS damage in rodents. Nat Methods 7: 701-8.
Gillani RL, Tsai S-Y, Wallace DG, O’Brien TE, Arhebamen E, Tole M, Schwab ME, Kartje GL. (2010) Cognitive recovery in the aged rat after stroke and anti-Nogo-A immunotherapy. Behavioural Brain Research 208: 415-424.
Petrinovic MM, Duncan CS, Bourikas D, Weinman O, Montani L, Schroeter A, Maerki D, Sommer L, Stoeckli ET, Schwab ME (2010) Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development 137: 2539-2550.
Gonzenbach RR, Gasser P, Zörner B, Hochreutner E, Dietz V, Schwab ME (2010) Nogo-A antibodies and training reduce muscle spasms in spinal cord-injured rats. Ann Neurol 68:48-57.
Mathis C, Schröter A, Thallmair M and Schwab ME (2010) Nogo-A regulates neural precursor migration in the embryonic mouse cortex. Cerebral Cortex 20:2380-2390
Kilic E, Elali A, Kilic U, Guo Z, Ugur M, Uslu U, Bassetti CL, Schwab ME, Hermann DM (2010) Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J Cereb Blood Flow Metab 30:969-984.
Joset A, Dodd DA, Halegoua S and Schwab ME (2010) Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling. J Cell Biol 188:271-285.
Willi R, Weinmann O, Winter C, Klein J, Sohr R, Schnell L, Yee BK, Feldon J, Schwab ME (2010) Constitutive genetic deletion of the growth regulator Nogo-A induces schizophrenia-related endophenotypes. J Neurosci 30:556-567.
Ghosh A, Haiss F, Sydekum E, Schneider R, Gullo M, Wyss MT, Mueggler T, Baltes C, Rudin M, Weber B, Schwab ME (2010) Rewiring of hindlimb corticospinal neurons after spinal cord injury. Nat Neurosci 13:97-104.
2009
Ghosh A, Sydekum E, Haiss F, Peduzzi S, Zorner B, Schneider R, Baltes C, Rudin M, Weber B, Schwab ME (2009) Functional and anatomical reorganization of the sensory-motor cortex after incomplete spinal cord injury in adult rats. J Neurosci 29:12210-12219. PDF
Maier IC, Ichiyama RM, Courtine G, Schnell L, Lavrov I, Edgerton VR, Schwab ME (2009) Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury. Brain. 2009 132:1426-40. PDF
Montani L, Gerrits B, Gehrig P, Dimou L, Wollscheid B, Schwab ME (2009) Neuronal Nogo-A modulates growth cone motility via RhoGTP/LIMK1/cofilin in the unlesioned adult nervous system. J Biol Chem 284: 10793-807. PDF
Arvanian VL, Schnell L, Lou L, Golshani R, Hunanyan A, Ghosh A, Pearse DD, Robinson JK, Schwab ME, Fawcett JF, Mendell LM (2009) Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fibers to motoneurons. Exp Neurol 216:471–480. PDF
Caelers A, Monge A, Michael J, Schwab ME, Bodmer D (2009) Nogo in the Mammalian cochlea. Otol Neurotol 30:668-675 PDF
Freund P, Schmidlin E, Wannier T, Bloch J, Mir A, Schwab ME, Rouiller EM (2009) Anti-Nogo-A antibody treatment promotes recovery of manual dexterity after unilateral cervical lesion in adult primates – re-examincation and extension of behavioral data. Eur J Neurosci 29:983–996 PDF
Willi R, Aloy EM, Yee BK, Feldon J, Schwab ME (2009) Behavioral characterization of mice lacking the neurite growth inhibitor Nogo-A. Genes Brain Behav 8:181–192. PDF
Sydekum E, Baltes C, Ghosh A, Mueggler T, Schwab ME, Rudin M (2009) Functional reorganization in rat somatosensory cortex assessed by fMRI: Elastic image registration based on structural landmarks in fMRI images and application to spinal cord injured rats. Neuroimage 44: 1345-1354. PDF
2008
Craveiro LM, Hakkoum D, Weinmann O, Montani L, Stoppini L, Schwab ME (2008) Neutralization of the membrane protein Nogo-A enhances growth and reactive sprouting in established organotypic hippocampal slice cultures. Eur J Neurosci 28: 1808-1824. PDF
Maier IC, Baumann K, Thallmair M, Weinmann O, Scholl J, Schwab ME (2008) Constraint-induced movement therapy in the adult rat after unilateral corticospinal tract injury. J Neurosci 28:9386-9403. PDF
Cheatwood JL, Emerick AJ, Schwab ME, Kartje GL (2008) Nogo-A Expression After Focal Ischemic Stroke in the Adult Rat. Stroke 39:2091-2098. PDF
Pernet V, Joly S, Christ F, Schwab ME (2008) Nogo-A and MAG differently regulate oligodendrocyte maturation and myelin formation. J Neurosci 28:7435-44. PDF
Wannier-Morino P, Schmidlin E, Freund P, Belhaj-Saif A, Bloch J, Mir A, Schwab ME, Roullier EM, Wannier T (2008) Fate of rubrospinal neurons after unilateral section of the cervical spinal cord in adult macaque monkeys: Effects of an antibody treatment neutralizing Nogo-A. Brain Res 1217:96-109. PDF
Endres M, Engelhardt B, Koistinaho J, Lindvall O, Mohr JP, Planas A, Schwaninger M, Schwab ME, Vivien D, Dirnagl U (2008) Improving outcome after stroke: overcoming the translational roadblock. Cerebrovasc Dis 25:268-278.
Bourquin C, van der Haar ME, Anz D, Sandholzer N, Neumaier I, Endres S, Skerra A, Schwab ME, Linington, C (2008) DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune. Eur J Pharmacol 588:99-105. PDF
Brenneman MM, Wagner SJ, Cheatwood JL, Heldt SA, Corin JV, Reep RL, Kartje GL, Mir AK, Schwab ME (2008) Nogo-A inhibition induces recovery from neglect in rats. Behav Brain Res 5:262-72. PDF
Dupuis L, Pehar M, Cassina P, Rene F, Castellanos R, Rouaux C, Gandelman M, Dimou L, Schwab ME (2008) Nogo receptor antagonizes p75NTR-dependent motor neuron death. Proc Natl Acad Sci USA 15:740-5. PDF
Beaud ML, Schmidlin E, Wannier T, Freund P, Bloch J, Mir A, Schwab ME, Rouillier EM (2008) Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion. BMC Neurosci 14:5. PDF
Brenneman MM, Wagner SJ, Cheatwood JL, Heldt SA, Corwin JV, Reep RL, Kartje GL, Mir AK, Schwab ME (2008) Nogo-A inhibition induces recovery from neglect in rats. Behav Brain Res 187:262-72. PDF
Muellner A, Gonzenbach R, Weinmann O, Schnell L, Liebscher T, Schwab ME (2008) Lamina specific restoration of serotonergic projections after Nogo-A antibody treatment of spinal cord injury. Eur J Neurosci 27:326-333.PDF