Open Positions

Postdoctoral position in Neuroepigenetics

The lab of Neuroepigenetics of I. Mansuy at the University and ETH Zürich, Switzerland (Brain Research Institute) is looking for an experienced epigeneticist interested in neuroscience. The project aims at investigating the mechanisms underlying the impact of environmental factors on the genome and epigenome in relation to brain functions and behavior across generations. The purpose is to examine the effects of exposure on genome sequence, structure and activity including retrotransposition and chromatin looping, and their inheritance. The candidate should have solid theoretical and practical knowledge in genetics and epigenetics, and experience in advanced genome technologies. The candidate should have an interest in exploring novel rules linking the environment to the genome and the epigenome, and in translational research relevant for human health and diseases. She/he will join a pluridisciplinary team at the interface of epigenetics, neuroscience and bioinformatics using an approach based on environmentally and genetically-modified mouse models. A strong team spirit, high scientific creativity and motivation are desired. The University and ETH Zürich offer optimal working conditions, ample lab space and technological support, and a rich scientific environment with a large and active community.

Women candidates are strongly encouraged to apply. This 3-5 year position is available in spring 2019 or anytime later in the lab of Prof I. Mansuy, University/ETH Zürich, Brain Research Institute, Irchel Campus, Zürich, Switzerland. Applications including a detailed cv, letter of motivation and scientific track record should be sent to Isabelle Mansuy: mansuy@hifo.uzh.ch.

Master´s position in Epigenetics-UZH/ETHZ

The laboratory of Neuroepigenetics at the Brain Research Institute, University Zürich and the Institute of Neuroscience, ETH Zürich is looking for a master student in cell and molecular biology to work on a project in epigenetics. The project aims to study the plasticity of epigenetic marks in germ cells and determine how changes in these marks can affect genome activity. The goal is to establish a method to assess chromatin accessibility in mouse sperm cells based on methylATAC-seq, a novel technique in epigenetics. The project will also involve methods like quantitative PCR, pyrosequencing, Western blotting and some bioinformatics. The project requires basic knowledge in genetics and epigenetics, and wet lab experience in basic molecular and cellular techniques. Knowledge in reproductive biology is an advantage. The student will work in an international research team and will be guided and supervised by a doctoral student.

The position is for 6-12 months, starting any time from now, and is in the lab of Prof. I. Mansuy, University/ETH Zürich, Irchel Campus, Zürich. Applications including a detailed CV and a letter of motivation should be sent to Martin Roszkowski: roszkowski@hifo.uzh.ch or Isabelle Mansuy: mansuy@hifo.uzh.ch.