Navigation auf


Brain Research Institute



Rupprecht P, Duss SN, Becker D, Lewis CM, Bohacek J, Helmchen F (2022) Centripetal integration of past events by hippocampal astrocytes and its regulation by the locus coeruleus. bioRxiv. doi:

Masala N, Mittag M, Ambrad Giovannetti E, O'Neil DA, Distler FJ, Rupprecht P, Helmchen F, Yuste R, Fuhrmann M, Beck H, Wenzel M, Kelly T (2023) Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adenoviral expression of Ca2+ indicators. bioRxiv. doi:

O’Neill PS, Baccino-Calace M, Rupprecht R, Friedrich RW, Muller M, Delvendahl I (2023) Deep learning-based synaptic event detection. bioRxiv. doi:

Groos D, Reuss AM*, Rupprecht P*, Stachniak T, Han S, Lewis CM, Sych Y, Wieckhorst M, Karayannis T, Aguzzi A, Helmchen F (2023) Distinct hypothalamus-habenula circuits govern risk preference. bioRxiv. doi: (*equal contribution)

Peer-reviewed publications

Rupprecht P, Carta S, Hoffmann A, Echizen M, Kitamura K, Helmchen F§, Friedrich RW§ (2021) A deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging data. Nature Neuroscience. 24(9):1324-1337. link (§ co-senior authors)

Schoenfeld G*, Carta S*, Rupprecht P, Ayaz A, Helmchen F (2021). In vivo calcium imaging of CA3 pyramidal neuron populations in adult mouse hippocampus. eNeuro. 8(4):ENEURO.0023-21.2021. link (* equal contribution)

Huang KH, Rupprecht P, Frank T, Kawakami K, Bouwmeester T, Friedrich RW (2020). A virtual reality system to analyze neural activity and behavior in adult zebrafish. Nature Methods. 17(3), 343-351. link

Rupprecht P, Friedrich RW (2018). Precise synaptic balance in the zebrafish homolog of olfactory cortex. Neuron 100(3), 669-683. link

Berens P, Freeman J, Deneux T, Chenkov N, McColgan T, Speiser A, Macke JH, Turaga SC, Mineault P, Rupprecht P, Gerhard S, Friedrich RW, Friedrich J, Paninski L, Pachitariu M, Harris KD, Bolte B, Machado TA, Ringach D, Stone J, Rogerson LE, Sofroniew NJ, Reimer J, Froudarakis E, Euler T, Roso MR, Theis L, Tolias AS, Bethge M (2018). Community-based benchmarking improves spike rate inference from two-photon calcium imaging data. PLoS Computational Biology 14(5), e1006157. link

Jacobson GA, Rupprecht P, Friedrich RW (2018). Experience-dependent plasticity of odor representations in the telencephalon of zebrafish. Current Biology 28(1), 1-14. link

Rupprecht P, Prendergast A, Wyart C, Friedrich RW (2016). Remote z-scanning with a macroscopic voice coil motor for fast 3D multiphoton laser scanning microscopy. Biomedical Optics Express 7(5), 1656-1671. link

Rupprecht P, Prevedel R, Groessl F, Haubensak WE, Vaziri A (2015). Optimizing and extending light-sculpting microscopy for fast functional imaging in neuroscience. Biomedical Optics Express 6(2), 353-368. link

Rupprecht P, Golé L, Rieu JP, Vézy C, Ferrigno R, Mertani HC, Riviere C (2012). A tapered channel microfluidic device for comprehensive cell adhesion analysis, using measurements of detachment kinetics and shear stress-dependent motion. Biomicrofluidics 6(1), 014107. link